Nobiletin

SKU: orb1304961

Description

Nobiletin is a polymethoxylated flavone derived from citrus peels, exhibiting anti-inflammatory and anti-tumor properties. It is used in research on cancer, inflammation, and metabolic diseases, with studies conducted in both cellular and animal models to investigate its mechanisms of action.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 478-01-3
• MW: 402.39
• Purity: 99.63%
• Formula: C₂₁H₂₂O₈
• SMILES: COc1ccc(cc1OC)-c1cc(=O)c2c(OC)c(OC)c(OC)c(OC)c2o1
• Target: Reactive Oxygen Species,Apoptosis,ROR,Autophagy,MMP
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.97 mM);Ethanol:3 mg/mL (7.46 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:73 mg/mL (181.42 mM)

Bioactivity

• In Vivo:
  LD50: 780 mg/kg (i.g.).

Storage & Handling

• Storage: keep away from moisture,store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

Reactive Oxygen Species, ReactiveOxygenSpecies, RAR-related orphan receptor, ROR, Apoptosis, Autophagy, Inhibitor, Hexamethoxyflavone, inhibit, MMP, Nobiletin

Compound Identifiers

PubChem CID

72344