Nicardipine

SKU: orb1306351

Description

Nicardipine is a dihydropyridine calcium channel blocker used in research to study hypertension and angina. It is widely applied in cardiovascular research, serving as a key pharmacological tool for in vitro and in vivo investigations of vascular smooth muscle contraction and calcium signaling pathways.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 55985-32-5
• MW: 479.52
• Purity: 99.56% (May vary between batches)
• Formula: C₂₆H₂₉N₃O₆
• SMILES: COC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OCCN(C)Cc1ccccc1
• Target: Calcium Channel
• Solubility: H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.17 mM);DMSO:250 mg/mL (521.35 mM)

Bioactivity

• Target IC50:
  Ca2+ channel (Cardiac):1 μM (IC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Dagan, CalciumChannel, Ca2+ channels, Ca channels, calcium channel, Calcium Channel, cardiac, Cardene, blood, blocker, Antagonil, angina, Flusemide, Inhibitor, inhibit, Nicardipine, YC93, YC-93, YC 93, pressure

Compound Identifiers

PubChem CID

4474