NHERF1 antibody

• Catalog Number: orb154204
• Category: Antibodies
• Description: Rabbit polyclonal antibody to NHERF1. NHERF1 is a sodium/hydrogen exchanger regulatory cofactor. It interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. NHERF1 also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. It localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in NHERF1 result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this protein is implicated in breast cancer.
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG
• Immunogen: Recombinant fusion protein of human SLC9A3R1(NP_004243.1).
• Dilution range: WB: 1:1000-4000
• Conjugation: Unconjugated
• MW: 50kDa
• UniProt ID: O14745
• Storage: Store at -20°C. Avoid freeze / thaw cycles.
• Buffer/Preservatives: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Alternative names: anti EBP50 antibody, anti NHERF antibody, anti NHE
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of extracts of various cells using NHERF1 antibody