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Neuroprotective agent 5
Catalog Number: orb2664873
| Catalog Number | orb2664873 |
|---|---|
| Category | Small Molecules |
| Description | Neuroprotective agent 5 (compound 28) acts as a brain-penetrating agent with anti-neuroinflammatory, antioxidant, and neuroprotective properties. It exhibits potent inhibition of nitric oxide (NO) with an EC50 of 0.49 μM and suppresses the release of pro-inflammatory mediators PGE2 and TNF-α. Additionally, it downregulates the expression of iNOS and COX-2 proteins, facilitating the polarization of BV-2 cells from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype. Neuroprotective agent 5 also dose-dependently inhibits acetylcholinesterase (AChE) activity and the aggregation of Aβ42. This compound is useful for research into Alzheimer's disease. |
| Purity | 98.00% |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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5-Hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone [orb1941483]
98.00%
357637-15-1
282.29
C17H14O4
50 mg, 5 mg
