Neuroligin 3 antibody

• Catalog Number: orb151019
• Category: Antibodies
• Description: Mouse monoclonal to Neuroligin 3 (ATTO-390). Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses..
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: S110-29
• Tested applications: ICC, IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG1
• Immunogen: Fusion protein amino acids 730-848 (intracellular C-terminus) of rat Neuroligin-3. Mouse: 99% identity (118/119 amino acids identical). Human: 98% identity (116/119 amino acids identical) ~60% identity with Neuroligin-1. ~40% identity with Neuroligin-2.
• Concentration: 1 mg/ml
• Dilution range: WB (1:1000)
• Conjugation: ATTO-390
• MW: 110kDa
• Target: Neuroligin 3
• Entrez: 171297
• UniProt ID: Q62889
• NCBI: AAA97871
• Storage: Conjugated antibodies should be stored at 4°C
• Buffer/Preservatives: PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated
• Alternative names: Gliotactin homolog antibody, Neuroligin-3 antibody
• Note: For research use only
• Application notes: 1 µg/ml of SMC-471 was sufficient for detection of Neuroligin 3 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
• Expiration Date: 12 months from date of receipt.