Netrin G1/NTNG1 Protein, Human, Recombinant (His)

• Catalog Number: orb1959420
• Category: Proteins
• Description: NTNG1 (Netrin G1) is a Protein Coding gene. This gene encodes a preproprotein that is processed into a secreted protein containing eukaryotic growth factor (EGF)-like domains. NTNG1 is broadly expressed in the brain, kidney, and other tissues. Netrins including NTNG1 are known to be axon guidance factors in the developing brain. It is involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular, and synaptic levels. The NTNG1 protein has an important role in the developing central nervous system, particularly in axonal guidance, signaling, and NMDA receptor function, and was a good candidate gene for Rett syndrome (RTT). They could be very important contributors to the genetic risk for psychosis.
• Tag: C-His
• Purity: 98.00%
• MW: 45.8 kDa (predicted)
• UniProt ID: Q9Y2I2
• Expression System: HEK293 Cells
• Biological Origin: Human
• Biological Activity: NTNG1 (Netrin G1) is a Protein Coding gene. This gene encodes a preproprotein that is processed into a secreted protein containing eukaryotic growth factor (EGF)-like domains. NTNG1 is broadly expressed in the brain, kidney, and other tissues. Netrins including NTNG1 are known to be axon guidance factors in the developing brain. It is involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular, and synaptic levels. The NTNG1 protein has an important role in the developing central nervous system, particularly in axonal guidance, signaling, and NMDA receptor function, and was a good candidate gene for Rett syndrome (RTT). They could be very important contributors to the genetic risk for psychosis.
• Expression Region: A DNA sequence encoding the human NTNG1 (NP_055732.2) (Met1-Gly408) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Val 19
• Storage: -20°C
• Note: For research use only
• Application notes: A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
• Expiration Date: 6 months from date of receipt.