Nepafenac

SKU: orb1309140

Description

Nepafenac is a nonsteroidal anti-inflammatory compound (NSAID) that acts as a cyclooxygenase (COX) inhibitor. It is used in research to study ocular inflammation and pain, with applications in both in vitro enzyme assays and in vivo models of postoperative inflammation.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 78281-72-8
• MW: 254.28
• Purity: 98.16% (May vary between batches)
• Formula: C₁₅H₁₄N₂O₂
• SMILES: NC(=O)Cc1cccc(C(=O)c2ccccc2)c1N
• Target: COX
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:60 mg/mL (235.96 mM)

Bioactivity

• Target IC50:
  COX-1:64.3 μM (IC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Nepafenac, COX-1, COX, COX-2, Cyclooxygenase, AHR 9434, AHR9434, AHR-9434, AL6515, AL-6515, AL 6515

Compound Identifiers

PubChem CID

151075