NCOA1 antibody

• Catalog Number: orb66875
• Category: Antibodies
• Description: Rabbit polyclonal to NCOA1.NCOA1 is a nuclear receptor coactivator that directly binds nuclear receptors and stimulates thetranscriptional activities in a hormone-dependent fashion. NCOA1 is involved in the coactivation ofvarious nuclear receptors, such as for steroids (PGR, GR and ER), retinoids XRs), thyroid hormone(TRs) and prostanoids (PPARs). NCOA1 is also involved in coactivation mediated by STAT3,STAT5A, STAT5B and STAT6 transcription factors. NCOA1 displays histone acetyltransferase activitytoward H3 and H4, and plays a central role in creating multisubunit coactivator complexes that act byboth chromatin remodeling and recruient of general transcription factors.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: N-terminal region of human NCOA1
• Dilution range: WB:1:1000-1:5000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 157
• UniProt ID: Q15788
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-NCOA1 antibody,anti-Nuclear receptor coactiva
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human 293T using NCOA1 antibody