NBD-GPP

SKU: orb65078

Description

NBD-GPP is a fluorescent analog of geranyl pyrophosphate (GPP). It serves as lipid donor for farnesyltransferase (FTase)-one of the three mammalian protein prenyltransferases. The attachment of the NBD-geranyl group to protein substrates allows for efficient fluorescence based FTase activity assays and inhibitor screening.

Images & Validation

• Application Notes:
  Spectroscopic Propertie: λexc 480 nm, λem 530 nm, ε 11.0 L mmol-1 cm-1 (pH 7.5).

Key Properties

• Molecular Weight: Theoretical MW: 492.31 g/mol
• Purity: ≥ 95% (HPLC)
• Formula: C₁₆H₂₂N₄O₁₀P₂
• SMILES: c1(ccc(c2c1non2)[N+](=O)[O-])NC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C

Storage & Handling

• Storage: store at -20 °C
• Form/Appearance: liquid (Supplied as 1 mM solution in 25 mM (NH 4)2CO3)
• Concentration: 1 mM
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

3,7-dimethyl-8-(7-nitro-benzo[1,2,5]oxadiazol-4-ylamino),-octa-2,6-diene-1-pyrophosphate, Fluorescent lipid donor for protein farnesyltransferase (FTase)

Compound Identifiers

PubChem CID

25141079