NBD-FPP

SKU: orb65157

Description

NBD-FPP is a fluorescent analog of farnesyl pyrophosphate (FPP). It serves as lipid donor for geranylgeranyltransferases (RabGGTase, GGTase-I). NBD-FPP changes its fluorescence upon binding to protein substrates and allows for efficient fluorescence based GGTase activity assays and inhibitor screening.

Images & Validation

• Application Notes:
  Spectroscopic Propertie: λexc 480 nm, λem 530 nm, ε 11.0 L mmol-1 cm-1 (pH 7.5).

Key Properties

• Molecular Weight: Theoretical MW: 560.43 g/mol
• Purity: ≥ 95% (HPLC)
• Formula: C₂₁H₃₀N₄O₁₀P₂
• SMILES: c1(ccc(c2c1non2)[N+](=O)[O-])NC/C(=C/CC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)/C

Storage & Handling

• Storage: store at -20 °C
• Form/Appearance: liquid (Supplied as 1 mM solution in 25 mM (NH 4)2CO3)
• Concentration: 1 mM
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

{3,7,11-trimethyl-12-(7-nitro-benzo[1,2,5]oxadiazo-4-ylamino),-dodeca-2,6,10-trien-1}pyrophosphate, Fluorescent lipid donor for protein geranylgeranyltransferases (RabGGTase, GGTase-I)

Compound Identifiers

PubChem CID

25141081