MZF1 Antibody / Myeloid zinc finger 1

• Catalog Number: orb1824627
• Category: Antibodies
• Description: Zinc finger genes that encode metal-binding proteins are transcriptional regulators of other genes. Myeloid zinc finger 1 (MZF-1), also designated zinc finger protein 42, and transcription factor ZBP-89, also designated zinc finger protein 148, belong to the Kruppel C2H2-type zinc-finger protein family. The gene encoding for the MZF-1 protein maps to chromosome 19q13.43 while the gene encoding for ZBP-89 is localized on chromosome 3q21. These proteins are nuclear proteins involved in the regulation of transcriptional events. MZF-1 regulates transcription during hemopoietic development and plays a role in myeloid cell differentiation. MZF-1 regulates the CD34 promoter in a tissue-specific manner. MZF-1 and FHL3 can form a complex of high molecular mass with other proteins in the nucleus. It is induced by retinoic acid and is primarily expressed in differentiating myeloid cells.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: PCRP-MZF1-1E8
• Tested applications: FACS, IF, IHC-P
• Reactivity: Human
• Isotype: Mouse IgG2a
• Immunogen: A recombinant partial protein sequence (within amino acids 37-128) from the human protein was used as the immunogen for the Myeloid zinc finger 1 antibody.
• Dilution range: Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This Myeloid zinc finger 1 antibody is available for research use only.
• UniProt ID: P28698
• Storage: Aliquot the Myeloid zinc finger 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.