You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb107771 |
---|---|
Category | Proteins |
Description | Interleukin-36 receptor antagonist (IL-36RA) is a secreted protein which belongs to the interleukin 1 cytokine family (IL-1family) and it is predominantly expressed in keratinocytes but not in fibroblasts, endothelial cells or melanocytes.IL-36RA hasbeen reported to antagonize the biological activity of IL-36alpha (IL-1F6), IL-36beta (IL-1F8), and IL-36gamma (IL-1F9). Furthermore, itcould constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonistand interleukin-1 receptor type I (IL-1R1). In addition, The receptor for IL-36RA has not been positively identified. Indirectevidence suggests it is IL-1Rrp2. Recombinant murine interleukin-36 RA contains 154 amino acid residues and it shares 91 %a.a. sequence identity with human IL-36RA. |
Tested applications | HPLC, SDS-PAGE |
Purity | > 95 % by SDS-PAGE and HPLC analyses |
Conjugation | Unconjugated |
MW | 16.9 kDa |
Target | IL-36RA |
Protein Sequence | VLSGALCFRM KDSALKVLYL HNNQLLAGGL HAEKVIKGEE ISVVPNRALD ASLSPVILGVQGGSQCLSCG TEKGPILKLE PVNIMELYLG AKESKSFTFY RRDMGLTSSF ESAAYPGWFLCTSPEADQPV RLTQIPEDPA WDAPITDFYF QQCD |
Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
Buffer/Preservatives | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, 2mM beta -mercaptoethanol |
Alternative names | Murine Interleukin-36 Receptor Antagonist Protein Read more... |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
HPLC, SDS-PAGE | |
Unconjugated | |
> 95 % by SDS-PAGE and HPLC analyses | |
20.9 kDa |
HPLC, SDS-PAGE | |
Unconjugated | |
> 95 % by SDS-PAGE and HPLC analyses | |
16.8 kDa |
Filter by Rating