MRPL44 Protein, Human, Recombinant (His)

• Catalog Number: orb1955652
• Category: Proteins
• Description: MRPL44 (Mitochondrial Ribosomal Protein L44) is a Protein Coding gene. MRPL44 encodes a protein in the large subunit of the mitochondrial ribosome and is suggested to locate near the tunnel exit of the yeast mitochondrial ribosome. It belongs to the mitochondrion-specific ribosomal protein mL44 subfamily. In the patient fibroblasts, decreased MRPL44 affected assembly of the large ribosomal subunit and stability of 16S rRNA leading to complex IV deficiency. It may have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome. MRPL44 is widely expressed in the bone marrow, lymph node, and other tissues. Diseases associated with MRPL44 include Combined Oxidative Phosphorylation Deficiency 16 and Combined Oxidative Phosphorylation Deficiency 1.
• Tag: C-His
• Purity: 98.00%
• MW: 35.7 kDa (predicted); 40 kDa (reducing conditions)
• UniProt ID: Q9H9J2
• Expression System: Baculovirus Insect Cells
• Biological Origin: Human
• Biological Activity: MRPL44 (Mitochondrial Ribosomal Protein L44) is a Protein Coding gene. MRPL44 encodes a protein in the large subunit of the mitochondrial ribosome and is suggested to locate near the tunnel exit of the yeast mitochondrial ribosome. It belongs to the mitochondrion-specific ribosomal protein mL44 subfamily. In the patient fibroblasts, decreased MRPL44 affected assembly of the large ribosomal subunit and stability of 16S rRNA leading to complex IV deficiency. It may have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome. MRPL44 is widely expressed in the bone marrow, lymph node, and other tissues. Diseases associated with MRPL44 include Combined Oxidative Phosphorylation Deficiency 16 and Combined Oxidative Phosphorylation Deficiency 1.
• Expression Region: A DNA sequence encoding the human MRPL44 (Q9H9J2) (Met1-Ser332) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Val 31
• Storage: -20°C
• Note: For research use only
• Application notes: A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
• Expiration Date: 6 months from date of receipt.