Mouse Mesothelin / MSLN (298-600) Protein

• Catalog Number: orb668889
• Category: Proteins
• Description: Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
• Reactivity: Mouse
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 36.0 kDa
• Target: Mesothelin
• Protein Sequence: NP_061345.1
• Source: Mouse Mesothelin (298-600), His Tag (orb668889) is expressed from human 293 cells (HEK293). It contains AA Asp 298 - Ser 600 (Accession # Q61468-1).
• Expression System: HEK293
• Expression Region: Asp 298 - Ser 600
• Endotoxins: 1.0 EU per μg
• NCBI: NP_061345.1
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: MSLN,Mesothelin,MPF
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.0 kDa. The protein migrates as 42-48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.