Mouse LIGHT / TNFSF14 Protein, His Tag, active trimer, low endotoxin (MALS verified)

• Catalog Number: orb1786126
• Category: Proteins
• Description: Tumor necrosis factor ligand superfamily member 14(LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell co-stimulation signals effecting CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmune-like disease syndromes.
• Reactivity: Mouse
• Tag: N-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 58.9 kDa
• Target: LIGHT
• UniProt ID: Q9QYH9
• Source: Mouse LIGHT Protein, His Tag (orb1786126) is expressed from human 293 cells (HEK293). It contains AA Asp 72 - Val 239 (Accession # Q9QYH9-1).
• Expression System: HEK293
• Expression Region: Asp 72 - Val 239
• Endotoxins: 1.0 EU per μg
• Storage: -20°C
• Buffer/Preservatives: PBS, pH 7.4
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 58.9 kDa. The protein migrates as 55-60 kDa and 65-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.