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Catalog Number | orb1786141 |
---|---|
Category | Tools |
Description | Interleukin-5 receptor subunit alpha (IL5RA) is also known as IL-5 receptor subunit alpha, IL-5R subunit alpha and CD125,which is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and type 5 subfamily.IL5R, a heterodimer of an alpha and a beta subunit, is expressed on eosinophils and basophils. IL5RA / CD125 is the receptor for interleukin-5 (IL5) and the alpha chain can bind to IL5. The WSXWS motif of IL5RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The beta subunit of IL5R is common to the IL3, IL5 and GM-CSF receptors. |
Tag | C-10×His |
Form/Appearance | Powder |
Conjugation | Unconjugated |
MW | 47.1 kDa |
Target | IL-5 R alpha |
UniProt ID | P21183 |
Source | Mouse IL-5 R alpha / CD125 Protein, His Tag (orb1786141) is expressed from human 293 cells (HEK293). It contains AA Asp 18 - His 339 (Accession # P21183). |
Expression System | HEK293 |
Expression Region | Asp 18 - His 339 |
Storage | -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.1 kDa. |
Expiration Date | 12 months from date of receipt. |
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