Mouse GITR / TNFRSF18 Protein

Catalog Number: orb334895

Catalog Number	orb334895
Category	Proteins
Description	Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Reactivity	Mouse
Tag	C-8×His
Form/Appearance	Powder
Purity	95%
Conjugation	Unconjugated
MW	15.5 kDa
Target	GITR
UniProt ID	Q8C4K3
Protein Sequence	Ser 22 - His 153
Source	Mouse GITR, His Tag (orb334895) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - His 153 (Accession # Q8C4K3).
Expression System	HEK293
Expression Region	Ser 22 - His 153
Endotoxins	1.0 EU per μg
Storage	-20℃
Buffer/Preservatives	PBS, pH7.4
Alternative names	AITR,GITR,TNFRSF18,CD357 Read more...
Note	For research use only
Application notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.5 kDa.
Expiration Date	6 months from date of receipt.

SDS-PAGE analysis of Mouse GITR protein

Purity:	≥90% as determined by SDS-PAGE
Source:	This protein contains the mouse Tnfrsf18(Ser22-His153) was fused with the C-terminal Fc-His Tag and expressed in Mammalian cells.