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Catalog Number | orb1570926 |
---|---|
Category | Proteins |
Description | CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family. It is found on the surface of vascular adventitial cells and accessory vascular cells . CD39L1 is a Ca2+ and Mg2+ dependent enzyme that hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP > > ADP = UDP. CD39L1 plays a role in regulating thrombosis and inflammation . It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation. |
Reactivity | Mouse |
Tag | C-10×His |
Form/Appearance | Liquid |
Purity | 95% |
Conjugation | Unconjugated |
MW | 50.2 kDa |
Target | CD39L1/ENTPD2 |
Source | Mouse CD39L1 / ENTPD2 Protein, His Tag (orb1570926) is expressed from CHO cells. It contains AA Cys 26 - Ser 462 (Accession # O55026-1). |
Expression System | CHO |
Expression Region | Cys 26 - Ser 462 |
Endotoxins | 1.0 EU per μg |
Storage | -70℃ |
Buffer/Preservatives | 20mM Tris,150mM NaCl,pH7.5 |
Alternative names | CD39L1, NTPDase-2 Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.2 kDa. The protein migrates as 44-46 kDa and 64-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
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