Mouse CD38 Protein

• Catalog Number: orb511244
• Category: Proteins
• Description: CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
• Reactivity: Mouse
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 31.7 kDa
• Target: CD38
• Protein Sequence: NP_031672.2
• Source: Mouse CD38, His Tag (orb511244) is expressed from human 293 cells (HEK293). It contains AA Leu 45 - Thr 304 (Accession # P56528-1).
• Expression System: HEK293
• Expression Region: Leu 45 - Thr 304
• Endotoxins: 1.0 EU per μg
• NCBI: NP_031672.2
• Storage: -20℃
• Buffer/Preservatives: 50 mM MES, 100 mM NaCl, pH6.5
• Alternative names: CD38,T10,cADPr hydrolase 1
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 31.7 kDa. The protein migrates as 38-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.