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Mouse B7-H3 / CD276 Protein
Catalog Number: orb348819
| Catalog Number | orb348819 |
|---|---|
| Category | Proteins |
| Description | B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. |
| Reactivity | Mouse |
| Tag | C-Fc |
| Form/Appearance | Powder |
| Purity | 95% |
| Conjugation | Unconjugated |
| MW | 50.1 kDa |
| Target | B7-H3 (2Ig) |
| Protein Sequence | NP_598744 |
| Source | Mouse B7-H3, Fc Tag (orb348819) is expressed from human 293 cells (HEK293). It contains AA Val 29 - Phe 244 (Accession # NP_598744). |
| Expression System | HEK293 |
| Expression Region | Val 29 - Phe 244 |
| Endotoxins | 1.0 EU per μg |
| NCBI | NP_598744 |
| Storage | -20℃ |
| Buffer/Preservatives | Tris with Glycine, Arginine and NaCl, pH7.5 |
| Alternative names | B7-H3,CD276,B7 homolog 3 Read more... |
| Note | For research use only |
| Application notes | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.1 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Mouse B7-H3 protein
- Item 1 of 1
Mouse B7-H3 / CD276 Protein [orb383527]
Unconjugated
95%
25.4 kDa
Mouse B7-H3, His Tag (orb383527) is expressed from human 293 cells (HEK293). It contains AA Val 29 - Phe 244 (Accession # NP_598744).
100 μg, 1 mg 
Recombinant Mouse B7-H3/CD276 Protein, His Tag [orb1550759]
> 95% by SDS-PAGE.
KMP1730, Recombinant Mouse B7-H3/CD276 Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Val29-Phe244) of mouse B7-H3/CD276 (Accession #Q8VE98) fused with a 6×His Tag at the C-terminus.
500 μg, 50 μgRecombinant Mouse B7-h3/Cd276 Protein, No Tag [orb1552867]
≥90% as determined by SDS-PAGE
This protein contains the mouse Cd276(Val29-Phe244) was fused without Tag and expressed in Mammalian cells.
100 μg, 50 μg
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