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Catalog Number | orb334876 |
---|---|
Category | Proteins |
Description | Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases. |
Reactivity | Mouse |
Tag | C-Fc |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 49.0 kDa |
Target | 4-1BB Ligand |
Protein Sequence | NP_033430 |
Source | Mouse 4-1BB Ligand, Fc Tag (orb334876) is expressed from human 293 cells (HEK293). It contains AA Arg 104 - Glu 309 (Accession # NP_033430). |
Expression System | HEK293 |
Expression Region | Arg 104 - Glu 309 |
Endotoxins | 1.0 EU per μg |
NCBI | NP_033430 |
Storage | -20℃ |
Buffer/Preservatives | Tris with Glycine, Arginine and NaCl, pH7.5 |
Alternative names | 4-1BB Ligand,TNFSF9,CD137L Read more... |
Note | For research use only |
Application notes | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49.0 kDa. The protein migrates as 64-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Mouse 4-1BB Ligand protein
Line graph illustrates about the sensitivity range of Mouse 4-1BB Ligand protein using different concentrations
≥90% as determined by SDS-PAGE | |
This protein contains the mouse Tnfsf9(Arg104-Glu309) was fused with the N-terminal His Tag and expressed in Mammalian cells. |
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