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Catalog Number | orb401974 |
---|---|
Category | Small Molecules |
Description | Motesanib is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is appr 10-fold more selective for VEGFR than PDGFR and Ret. |
CAS Number | [453562-69-1] |
MW | 373.46 |
SMILES | O=C(C1=CC=CN=C1NCC2=CC=NC=C2)NC3=CC(NCC4(C)C)=C4C=C3 |
Formula | C22H23N5O |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[857876-30-3] | |
551.4325 | |
C22H27N5O8P2 |
> 98% (HPLC) | |
857876-30-3 |
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