Motesanib Diphosphate (AMG-706)

• Catalog Number: orb181060
• Category: Small Molecules
• Description: Motesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret.
• CAS Number: [857876-30-3]
• MW: 551.4325
• SMILES: C(NCC1C=CN=CC=1)1=NC=CC=C1C(NC1=CC2=C(C=C1)C(C)(C)CN2)=O.P(O)(O)(O)=O.P(O)(O)(O)=O
• Formula: C₂₂H₂₇N₅O₈P₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.