Monoamine Oxidase B inhibitor 5

SKU: orb2646156

Description

Monoamine OxidaseB inhibitor 5 (Compound 16d) is a reversible and selective inhibitor of monoamine oxidase B (hMAO-B), with an IC50 value of 67.3 nM and a Ki of 82.5 nM. It exhibits favorable pharmacokinetic properties and low toxicity in rat models. Additionally, this compound alleviates motor impairments in a Parkinson's mouse model induced by MPTP, and it is characterized by its ability to penetrate the blood-brain barrier (BBB).

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Key Properties

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CAS Number	2969160-15-2
MW	299.3
Formula	C₁₆H₁₄FN₃O₂
SMILES	O=C(N)CC1=NC=2C=CC(OCC3=CC=C(F)C=C3)=CC2N1
Target	Monoamine Oxidase

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Monoamine Oxidase

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