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Monoamine Oxidase B inhibitor 5

SKU: orb2646156

Description

Compound 16d is a potent, reversible, and selective hMAO-B inhibitor (IC50 = 67.3 nM) with demonstrated blood-brain barrier penetration. It shows favorable pharmacokinetics and reduces MPTP-induced motor deficits in murine Parkinson's models, supporting its use in neurodegenerative disease research.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2969160-15-2
MW299.3
FormulaC16H14FN3O2
SMILESO=C(N)CC1=NC=2C=CC(OCC3=CC=C(F)C=C3)=CC2N1
TargetMonoamine Oxidase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information