MOCOS antibody

• Catalog Number: orb67220
• Category: Antibodies
• Description: Rabbit polyclonal to MOCOS.Molybdenum cofactor sulfurase (MOCOS) belongs to the class-V pyridoxal-phosphate-dependentaminotransferase family. It sulfurates the molybdenum cofactor. Sulfation of molybdenum is essentialfor xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenumcofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain isable to reduce N-hydroxylated prodrugs, such as benzamidoxime. Defects in MOCOS are the causeof xanthinuria type 2 (XU2). Patients suffering XU2 cannot metabolize allopurinol into oxypurinol dueto dual deficiency of xanthine dehydrogenase and aldehyde oxidase.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: N-terminal region of human MOCOS
• Dilution range: WB:1:500-1:1000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 98
• UniProt ID: Q96EN8
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-MOCOS antibody,anti-Molybdenum cofactor sulfu
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human HepG2 using MOCOS antibody