MMP2 Antibody

• Catalog Number: orb1825293
• Category: Antibodies
• Description: It recognizes a protein of 72kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 4D3
• Tested applications: IHC-P
• Reactivity: Human
• Isotype: Mouse IgG1
• Immunogen: A recombinant human MMP2 protein fragment (within amino acids 557-569) was used as the immunogen for the MMP2 antibody.
• Dilution range: Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This MMP2 antibody is available for research use only.
• UniProt ID: P08253
• Storage: Aliquot the MMP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.