MLL5 antibody

• Catalog Number: orb66810
• Category: Antibodies
• Description: Rabbit polyclonal to MLL5.MLL5 is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family. It is a histonemethyltransferase that specifically mono-and dimethylates Lys-4 of histone H3 (H3K4me1 andH3K4me2). Lys-4 methylation of H3 represents a specific tag for epigenetic transcriptional activation.It is a key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulationof hematopoietic stem cell self-renewal by a mechanism that involves DNA methylation.Overexpression of MLL5 inhibits cell cycle progression while knockdown induces cell cycle arrest atboth the G1 and G2/M phases.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: N-terminal region of human MLL5
• Dilution range: WB:1:1000-1:5000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 205
• UniProt ID: Q8IZID2
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-MLL5 antibody,anti-FLJ10078 antibody,anti-FLJ
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela using MLL5 antibody