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Catalog Number | orb1298854 |
---|---|
Category | Small Molecules |
Description | ML318 |
Purity | 98.93% |
MW | 280.22 |
Biological Activity | ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions. |
CAS Number | 1610516-67-0 |
Formula | C14H8F4N2 |
SMILES | Fc1ccc(cc1)C(C#N)c1cccc(n1)C(F)(F)F |
Storage | -20°C |
Note | For research use only |