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Mirin

SKU: orb1226816

Description

A small molecule inhibitor of MRN (Mre11-Rad50-Nbs1) pathway that inhibits Mre11-associated exonuclease activity; prevents MRN-dependent activation of ATM (IC50=12 uM) without affecting ATM protein kinase activity; inhibits Mre11 nuclease activity at 100 uM, does not inhibit ExoIII nuclease activity; inhibits the G2 checkpoint, and blocks homology-directed repair (HDR) in mammalian cells.

Images & Validation

Key Properties

CAS Number1198097-97-0
MW220.2477
Purity>98% (HPLC)
FormulaC10H8N2O2S
SMILESO=C1NC(S/C1=C\C2=CC=C(O)C=C2)=N
TargetMRN
SolubilityDMSO: ≥ 31 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Mirin

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Quality Guarantee

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Mirin (orb1226816)

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% DMSO +
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%

Available Sizes

Select a size below

5 mg
$ 100.00
10 mg
$ 130.00
25 mg
$ 220.00
50 mg
$ 340.00
100 mg
$ 590.00
200 mg
$ 760.00
500 mg
$ 1,200.00