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Catalog Number | orb1691474 |
---|---|
Category | Small Molecules |
Description | Milvexian |
CAS Number | 1802425-99-5 |
Purity | 98% |
MW | 626.45 |
SMILES | C[C@@H]1CCC[C@@H](c2cc(ccn2)-c2c(NC1=O)cnn2C(F)F)n1cnc(cc1=O)-c1cc(Cl)ccc1-n1cc(Cl)nn1 |
Formula | C28H23Cl2F2N9O2 |
Biological Activity | Milvexian (BMS-986177) is a potent antithrombotic compound that inhibits human and rabbit factor XIa (FXIa) directly and reversibly. It is orally-bioavailable and exhibits a K i of 0.11 nM and 0.38 nM against human and rabbit FXIa, respectively. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |