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Catalog Number | orb1960096 |
---|---|
Category | Proteins |
Description | Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 14.03 kDa and the accession number is P12025. |
Tag | N-His |
Purity | 98.00% |
MW | 14.03 kDa (predicted). The protein migrates to 17-20 kDa based on Tris-Bis PAGE result. |
UniProt ID | P12025 |
Expression System | E. coli |
Biological Origin | Mouse |
Biological Activity | Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 14.03 kDa and the accession number is P12025. |
Expression Region | Lys23-Asp140 |
Storage | -20°C |
Note | For research use only |
Application notes | 0 |
Expiration Date | 6 months from date of receipt. |
98.00% | |
18 KDa (reducing condition) |
41.6 kDa (Predicted) |