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Catalog Number | orb1960665 |
---|---|
Category | Proteins |
Description | MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.. MICA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 35.8 kDa and the accession number is Q96QC4. |
Tag | C-His-Avi |
Purity | 98.00% |
MW | 35.8 kDa (predicted). Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result. |
UniProt ID | Q96QC4 |
Expression System | HEK293 Cells |
Biological Origin | Human |
Biological Activity | MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.. MICA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 35.8 kDa and the accession number is Q96QC4. |
Expression Region | Glu24-Gln308 |
Storage | -20°C |
Note | For research use only |
Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Expiration Date | 6 months from date of receipt. |
98.00% | |
35.8 kDa (predicted). Due to glycosylation, the protein migrates to 60-68 kDa based on Tris-Bis PAGE result. |