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Catalog Number | orb1958190 |
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Category | Small Molecules |
Description | MESDC2 Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | Approxiamtely 23.6 kDa |
Biological Activity | MESD (Mesoderm Development LRP Chaperone) is a Protein Coding gene. LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61, and MESDC2, is a member of the MESD family. It is widely expressed in the thyroid, placenta, and other tissues. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity resides in the N- and C-terminal unstructured regions. MESDC2 acts as a modulator of the Wnt pathway since some LDLRs are coreceptors for the canonical Wnt pathway. MESDC2 is essential for the specification of embryonic polarity and mesoderm induction. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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