Mereletinib (AZD-9291,Osimertinib)

• Catalog Number: orb180883
• Category: Small Molecules
• Description: AZD-9291 is a potent and selective mutated forms EGFR inhibitor(Exon 19 deletion EGFR IC50=12.92 nM, L858R/T790M EGFR IC50= 11.44 nM, wild type EGFR IC50= 493.8 nM).
• CAS Number: [1421373-65-0]
• MW: 499.6073
• SMILES: O(C([H])([H])[H])C1=C(C([H])=C(C(=C1[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])N([H])C(C([H])=C([H])[H])=O)N([H])C1=NC([H])=C([H])C(C2=C([H])N(C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C32)=N1
• Formula: C₂₈H₃₃N₇O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of Mereletinib (AZD-9291