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Catalog Number | orb746526 |
---|---|
Category | Antibodies |
Description | Mepolizumab (SB 240563) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma. |
Clonality | Monoclonal |
CAS Number | [196078-29-2] |
Antibody Type | Biosimilar Antibody |
Purity | > 98%,Standard References |
Conjugation | Unconjugated |
MW | 762.96624 |
SMILES | O[C@@H]1CC[C@@H](O[C@H]2[C@H](O)[C@@H](C(=O)O)O[C@@H](OC3CC[C@@]4([C@H]5CCC6=C7CC(C)(C)CC[C@@]7(CC[C@@]6(C)[C@]5(C)CC[C@H]4C3(C)C)C(=O)O)C)[C@@H]2O)[C@H](O)[C@H]1O |
Formula | C42H66O12 |
Target | Mepolizumab Biosimilar(Anti-IL-5 Reference Antibody) |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |