MAPKBP1 antibody

• Catalog Number: orb154035
• Category: Antibodies
• Description: Rabbit polyclonal antibody to MAPKBP1. MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP1 (mitogenactivated protein kinase binding protein 1), also known as JNKBP1, is a 1,514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptorassociated factor 2) and Tak1 (TGF beta activated kinase 1), MAPKBP1 is thought to act an adaptor protein for NFkB (nuclear factor kB) activation. MAPKBP1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, PraderWilli syndrome, TaySachs disease and Marfan syndrome are all associated with defects in chromosome 15localized genes.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ELISA, WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAPKBP1 (NP_001122080.1).
• Dilution range: WB: 1:200-500, IHC-P: 1:50-100
• Conjugation: Unconjugated
• MW: 164kDa
• UniProt ID: O60336
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Alternative names: anti JNKBP1 antibody, anti MGC138851 antibody, ant
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of extracts of mouse liver tissue using MAPKBP1 antibody

Immunohistochemical staining of mouse stomach tissue using MAPKBP1 antibody (dilution of 1:100)

Immunohistochemical staining of human stomach tissue using MAPKBP1 antibody (dilution of 1:100)