MAO-B-IN-26

• Catalog Number: orb1942899
• Category: Small Molecules
• Description: MAO-B-IN-26 (Compound IC9) is a dual MAO-B and acetylcholinesterase inhibitor that protects SH-SY5Y cells from Aβ-induced toxicity, including morphological alterations, reactive oxygen species (ROS) production, and membrane damage, while preventing Aβ-triggered autophagy and apoptosis, thus showing potential as a neuroprotective agent in Alzheimer's disease [1].
• CAS Number: 38470-71-2
• Purity: 98.00%
• MW: 326.19
• SMILES: C(/C=C/C1=CC=C(Br)C=C1)(=O)C=2C=3C(NC2)=CC=CC3
• Formula: C₁₇H₁₂BrNO
• Biological Activity: MAO-B-IN-26 (Compound IC9) serves as both a MAO-B and acetylcholinesterase inhibitor. It safeguards SH?SY5Y cells from Aβ-induced toxicity, including morphological alterations, reactive oxygen species (ROS) production, and membrane damage, while also preventing Aβ-triggered autophagy and apoptosis. As such, MAO-B-IN-26 holds potential as a neuroprotective agent in the context of Alzheimer’s disease [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.