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MAN1B1 Protein, Human, Recombinant (His)
Catalog Number: orb1960956
| Catalog Number | orb1960956 |
|---|---|
| Category | Small Molecules |
| Description | MAN1B1 Protein, Human, Recombinant (His) |
| Purity | 98.00% |
| MW | 58-80 KDa, reducing conditions |
| Biological Activity | Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning, it is also associated with impairments in adaptative behavior and manifested during the developmental period. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Recombinant Human MAN1B1 Protein, His Tag [orb1552051]
≥90% as determined by SDS-PAGE
This protein contains the human MAN1B1(Asp106-Ala699) was fused with the C-terminal His Tag and expressed in Mammalian cells.
100 μg, 50 μg
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