Macitentan (Actelion-1,ACT-064992)

• Catalog Number: orb146064
• Category: Small Molecules
• Description: macitentan (Actelion-1, ACT-064992) is an orally active, non-peptide dual endothelin (ET)A/B receptor antagonist with IC50 of 0.5 nM/391 nM.
• CAS Number: [441798-33-0]
• MW: 588.27
• SMILES: BrC1=CN=C(OCCOC2=C(C3=CC=C(Br)C=C3)C(NS(NCCC)(=O)=O)=NC=N2)N=C1
• Formula: C₁₉H₂₀Br₂N₆O₄S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of Macitentan (Actelion-1