LY487379

• Catalog Number: orb1687287
• Category: Small Molecules
• Description: LY487379
• CAS Number: [353231-17-1]
• Purity: 98%
• MW: 452.45
• SMILES: O=S(=O)(N(C1=CC=C(OC=2C=CC=CC2OC)C=C1)CC=3C=NC=CC3)CC(F)(F)F
• Formula: C₂₁H₁₉F₃N₂O₄S
• Biological Activity: LY487379 is a selective human mGluR2 positive allosteric modulator (PAM). LY487379 potentiates glutamate-stimulated [ 35 S]GTPγS binding with EC 50 values of 1.7 μM and > 10 μM for mGlu2 and mGlu3 receptors respectively. LY487379 promotes cognitive flexibility and facilitates behavioral inhibition in a rat model. LY487379 can be used for schizophrenia research [2].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.