LXRA antibody

• Catalog Number: orb67061
• Category: Antibodies
• Description: Rabbit polyclonal to LXRA.Liver X receptor alpha (LXRA) belongs to the nuclear hormone receptor family, NR1 subfamily. LXRAis an orphan receptor. LXRA can form a heterodimer with RXR, which shifts RXR from a silent DNAbindingpartner to an active ligand-binding subunit in mediating retinoid responses through targetgenes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats oftwo similar hexanuclotide half-sites spaced by four nucleotides. LXRA plays an important role in theregulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependentubiquitination of LDLR, VLDLR and LRP8.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse
• Immunogen: middle region of human LXRA
• Dilution range: WB:1:1000-1:5000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 50
• UniProt ID: Q13133
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-LXRA antibody,anti-Oxysterols receptor LXRalp
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from mouse liver using LXRA antibody