LRRC3B Protein, Human, Recombinant (hFc)

• Catalog Number: orb1959208
• Category: Small Molecules
• Description: LRRC3B Protein, Human, Recombinant (hFc)
• Purity: 98.00%
• MW: Approxiamtely 45.7 kDa
• Biological Activity: LRRC3B expression is downregulated in many kinds of malignant tumors and it is regarded as a tumor inhibition protein. The leucine-rich repeat-containing 3B (LRRC3B) gene is a putative tumor suppressor located on human chromosome 3 in the 3p24 region. LRRC3B is frequently altered in colon and gastric cancers and also in leukemias.LRRC3B expression is downregulated in lung cancer cell lines and LRRC3B could inhibit lung cancer cell proliferation, invasion, and cell cycle progress. LRRC3B could be a new target for lung cancer therapy.LRRC3B depletion in HBE cells promoted proliferation and invasion，suggesting that LRRC3B may serve as an important tumor suppressor in NSCLC.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.