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Loganin

SKU: orb1305061

Description

Loganin is an iridoid glucoside that acts as a cyclooxygenase-1 (COX-1) inhibitor and suppresses TNF-α production. It exhibits antioxidant free-radical-scavenging activity and inhibits melanogenesis, making it a compound of interest for research in inflammation, oxidative stress, and dermatology.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience, Signal Transduction

Images & Validation

Key Properties

CAS Number18524-94-2
MW390.38
Purity100.00% (May vary between batches)
FormulaC17H26O10
SMILESCOC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]2[C@@H](C)[C@@H](O)C[C@H]12
TargetApoptosis|||NF-κB|||AChR|||Cholinesterase (ChE)|||BACE
SolubilityDMSO:250 mg/mL (640.4 mM);H2O:20 mg/mL (51.23 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.12 mM)

Bioactivity

Target IC50
AChE:3.95 μM|BACE1:47.97 μM|BChE:33.02 μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

BACE1, BChE, Apoptosis, AChE, Inhibitor, Loganin, Loganoside, inhibit, NF-κB, NFkB, NFκB, NF-kB

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

5 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 110.00
25 mg
$ 160.00
50 mg
$ 260.00
100 mg
$ 340.00
500 mg
$ 770.00
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