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LJ570
Catalog Number: orb746495
| Catalog Number | orb746495 |
|---|---|
| Category | Small Molecules |
| Description | LJ570 is the first PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation. LJ570 is a potent partial agonist of both PPARα and γ subtypes. LJ570 inhibited the Cdk5-mediated phosphorylation of PPARγ at serine 273 that is currently considered the mechanism by which some PPARγ partial agonists exert antidiabetic effects similar to thiazolidinediones, without showing their typical side effects. LJ570 may be useful for treatment of dyslipidemic type 2 diabetes. |
| CAS Number | [2252488-69-8] |
| MW | 394.46 |
| SMILES | O=C([C@H](CC1C=CC(C2C=CC=CC=2)=CC=1)OC1C=CC(C2C=CC=CC=2)=CC=1)O |
| Formula | C27H22O3 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
LJ570 [orb1298989]
99.89%
2252488-69-8
394.46
C27H22O3
50 mg, 25 mg, 1 ml x 10 mm (in DMSO), 100 mg, 500 mg, 1 mg, 2 mg, 5 mg, 10 mg
