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Catalog Number | orb2703720 |
---|---|
Category | Antibodies |
Description | Lintuzumab (HUM-195) is an anti-CD33 humanized monoclonal antibody. Lintuzumab reduces the production of TNFα-induced pro-inflammatory cytokines and chemokines by AML cells. Lintuzumab promotes tumor cell killing through antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis (ADCP) activities against MDR? and MDR+ AML cell lines and primary AML patient samples. Lintuzumab enhances survival and reduces tumor burden in mice. |
Target | Lintuzumab Biosimilar(Anti-Siglec-3 / CD33 Reference Antibody) |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Antibody Type | Primary Antibody |
CAS Number | [166089-32-3] |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Note | For research use only |