LGR5 antibody

• Catalog Number: orb34047
• Category: Antibodies
• Description: Rabbit polyclonal antibody to LGR5 (leucine-rich repeat-containing G-protein coupled receptor 5), also known as GPR49 or GPR67, belongs to the G protein-coupled receptor family. It highly expressed in placenta, skeletal muscle and spinal cord.It plays an important role in embryonic growth control and cellular differentiation. Overexpression of LGR5 is associated with increased tumor susceptibility and malignant transformation, implicating LGR5 as a potent tumor-inducing protein.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Clone Number: RB14555
• Tested applications: FC, IHC-P, WB
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: Synthetic Peptide
• Dilution range: WB: 1:1000, IHC-P: 1:10-50, FACS: 1:10-50
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• MW: 99998
• Target: LGR5
• UniProt ID: O75473
• NCBI: NP_003658.1, NP_001264155.1
• Alternative names: Anti-Leucine-rich repeat-containing G-protein coup
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of HepG2 cell line lysates (35ug/lane) using LGR5 antibody

Flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram) using LGR5 antibody

Immunohistochemical analysis of formalin-fixed and paraffin-embedded human brain tissue using LGR5 antibody