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Catalog Number | orb2024735 |
---|---|
Category | Proteins |
Description | A 16-kDa peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Leptin provides the key afferent signal from fat cells in the feedback system that controls body fat stores. |
Form/Appearance | Lyophilized from concentrated solution with 0.02% NaHCO3 |
Purity | Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
MW | 16 kDa |
UniProt ID | O02720 |
Protein Sequence | The sequence of the first five N - terminal amino acids was determined and was found to be Ala - Val - Pro - Ile - Arg. |
Source | E. coli |
Biological Activity | Biological active as evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. |
NCBI | NP_001003070.1 |
Storage | It is recommended to reconstitute the lyophilized Leptin in sterile 0.4% NaHCO3 adjusted to pH 8-9, not less than 100 ug/mL, which can then be further diluted to other aqueous solutions. Lyophilized Leptin, although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Leptin should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze/thaw cycles. |
Buffer/Preservatives | Lyophilized from concentrated solution with 0.02% NaHCO3 |
Alternative names | OB Read more... |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
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