LDLR (N2) Antibody, Rabbit Polyclonal

SKU: orb66977

Description

Rabbit polyclonal to LDLR.The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved inreceptor-mediated endocytosis of specific ligands. LDLR is a single-pass membrane protein, whichbinds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells byendocytosis. LDLR can be ubiquitinated by MYLIP leading to its degradation. Mutations in LDLRcause the autosomal dominant disorder, familial hypercholesterolemia.

Research Area

Metabolism Research

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:1000-1:5000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human LDLR
• Molecular Weight: 95
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-LDLR antibody,anti-Lowdensity lipoprotein receptor antibody,anti-LDL receptor antibody

Quick Database Links

UniProt

P01130