LDLR (N2) Antibody, Rabbit Polyclonal

SKU: orb66977

Description

Rabbit polyclonal to LDLR.The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved inreceptor-mediated endocytosis of specific ligands. LDLR is a single-pass membrane protein, whichbinds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells byendocytosis. LDLR can be ubiquitinated by MYLIP leading to its degradation. Mutations in LDLRcause the autosomal dominant disorder, familial hypercholesterolemia.

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Tested Applications	WB
Dilution range	WB:1:1000-1:5000
Reactivity	Human

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	N-terminal region of human LDLR
Molecular Weight	95
Purity	Affinity purification

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

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anti-LDLR antibody,anti-Lowdensity lipoprotein receptor antibody,anti-LDL receptor antibody

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Western blot analysis of total cell extracts from human hepG2 using LDLR antibody

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UniProt

P01130

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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