LAR/PTPRF antibody

• Catalog Number: orb167656
• Category: Antibodies
• Description: Mouse monoclonal antibody to PTPRF (ATTO 594). PTPRF or leukocyte common antigen-related protein (LAR) is a widely expressed protein tyrosine phosphatase with an extracellular receptor region that resembles a cell adhesion molecule. PTPRF removes phosphate group from-catenin, an event that may subsequently facilitate cell-cell adhesion and ensure the stability of the cadherin complex. This phosphatase has also been implicated in various cellular processes such as neurite growth, nerve regeneration, actin remodeling and regulation of insulin function . Anti-PTPRF (C-terminal) antibody is specific for the extracellular and cytoplasmic subunits of human PTPRF (approx. 210, 150 and 85 kDa). Detection of the PTPRF bands by immunoblotting is specifically inhibited by the immunizing peptide.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: S165-38
• Tested applications: ICC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG2a
• Immunogen: Fusion protein amino acids 1315-1607 (cytoplasmic C-terminus) of human LAR. 97% identical in both rat and mouse. > 80% identity with PTPRD and PTPRS. > 50% identity with PTPRM and PTPRK.
• Concentration: 1 mg/ml
• Dilution range: WB (1:1000)
• Conjugation: ATTO-594
• MW: 85kDa
• Target: LAR
• Entrez: 5792
• UniProt ID: P10586
• NCBI: NP_002831.2
• Storage: Conjugated antibodies should be stored at 4°C
• Buffer/Preservatives: PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated
• Alternative names: FLJ43335 antibody, FLJ45062 antibody, FLJ45567 ant
• Note: For research use only
• Application notes: 1 µg/ml of SMC-443 was sufficient for detection of LAR/PTPRF in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
• Expiration Date: 12 months from date of receipt.