Larotrectinib (LOXO-101 free base)

• Catalog Number: orb611324
• Category: Small Molecules
• Description: LOXO-101 is a small molecule that was designed to block the ATP binding site of the TRK family of receptors, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases.
• CAS Number: [1223403-58-4]
• MW: 428.44
• SMILES: FC1C([H])=C([H])C(=C([H])C=1[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N1C1C([H])=C([H])N2C(=C(C([H])=N2)N([H])C(N2C([H])([H])C([H])([H])[C@@]([H])(C2([H])[H])O[H])=O)N=1)F
• Formula: C₂₁H₂₂F₂N₆O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.